Chapter 14
Gene Expression at the Molecular Level III: Gene Regulation
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Parts
- 1Why cells regulate their genes4 min
- 2Repressors, activators, and the lac operon4 min
- 3Switching the lac operon on and off4 min
- 4The trp operon and predicting mutations4 min
- 5Eukaryotic promoters and enhancers4 min
- 6General transcription factors and mediator3 min
- 7Remodeling chromatin and modifying histones3 min
- 8Switching genes on and silencing them4 min
- 9Regulating splicing and translation4 min
Key terms
- constitutive gene
- regulatory transcription factor
- repressor
- activator
- negative control
- positive control
- small effector molecule
- operon
- polycistronic mRNA
- lac operon
- operator
- lac repressor
- β-galactosidase
- inducer
- inducible operon
- catabolite activator protein
- catabolite repression
- trp operon
- corepressor
- repressible operon
- combinatorial control
- core promoter
- TATA box
- basal transcription
- enhancer
- general transcription factor
- TFIID
- mediator
- coactivator
- ATP-dependent chromatin-remodeling complex
- histone variant
- histone acetyltransferase
- histone code
- nucleosome-free region
- DNA methylation
- CpG island
- facultative heterochromatin
- splicing factor
- iron regulatory protein
- ferritin