Chapter 12
Gene Expression at the Molecular Level I: Production of mRNAs and Proteins
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Parts
- 1Genes, proteins, and the central dogma5 min
- 2How transcription works4 min
- 3Eukaryotic transcription and the ends of mRNA4 min
- 4Splicing out introns4 min
- 5The genetic code4 min
- 6Codons meet anticodons3 min
- 7Transfer RNA and the enzymes that load it3 min
- 8The ribosome3 min
- 9Starting translation and building the chain4 min
- 10Ending translation, and how antibiotics block it3 min
Key terms
- gene expression
- central dogma
- transcription
- translation
- mRNA
- protein-coding gene
- non-coding RNA
- tRNA
- rRNA
- pre-mRNA
- promoter
- terminator
- RNA polymerase
- sigma factor
- coding strand
- RNA polymerase II
- preinitiation complex
- 5′ cap
- poly A tail
- RNA splicing
- intron
- exon
- spliceosome
- alternative splicing
- genetic code
- codon
- degenerate
- start codon
- stop codon
- reading frame
- anticodon
- aminoacyl-tRNA synthetase
- charged tRNA
- ribosome
- A site
- P site
- E site
- peptidyl transfer reaction
- release factor
- polysome